Dear Bryan, Currently, I am testing a single ADS1255. Therefore, the raised issue does not apply. If I manage to make it work in two-wire mode with a UART, I will use the 8 serial ports of the Teensy 4.1 and declare another 4 software ones. This way, I will have the 12 channels I need. The Teensy 4.1 will then allow me to transmit the data over Ethernet using the TCP/IP protocol or simply via the dedicated serial interface to the PC. Giovanni
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