Hello Jeff, Thank you for your post. You should try to route the P and N channel input traces differentially, but the total impedance does not need to be tightly controlled. The overall impedance matching will be dominated by the passive component tolerances (namely the resistors and capacitors used for protection or antialiasing). The traces or ADS1299 itself does not necessarily require shielding. However, a solid ground plane below the device is recommended. Regards, Ryan
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