Hello Iouri, It seems like the inputs are floating when you take the measurements. Can you confirm your external power supply grounds are both connected to the local ground on the ADS127L11 board? With ANP(4)=3.5V and ANN(5)=2.5V, the ideal conversion code should be (3.5-2.5)/4.096*2^23=2048000, or 0x1F4000h. Regards, Keith
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